Generalized chrysiasis improved with pulsed dye laser.

Chrysiasis is the phenomenon of bluish to slategray skin pigmentation induced by prolonged treatment with gold salts. The most common etiology is the administration of gold salts to patients with rheumatoid arthritis. Although parental gold salt administration is now uncommon because of the availability of biologic agents and disease-modifying antirheumatic drugs, chrysiasis may still be seen because this condition can develop decades after discontinuing gold salts. Discoloration can persist for a lifetime.